Sanchezburgos r, gonzalezmartinmoro j, perezfernandez e, burguenogarcia m. This newly updated classification adopts a simpler format of the germ cell layer of origin such as epithelial, mesenchymal ectomesenchymal and. A 19year audit of benign jaw tumours and tumourlike. Rightfully called the master of disguise, this lesion has been known for its varied clinical and histoarchitectural patterns. Benign mesenchymal odontogenic tumours odontogenic. A thirteenyear retrospective analysis of 179 odontogenic.
New findings in odontogenic tumors e557 1% of all ot in most of the published series worldwide. The last who classification of odontogenic tumors was 9 years ago and it is time for revision. These tumours are believed to take origin from the epithelial components of the odontogenic. We offer the following critique as a constructive, thought provoking challenge to those chosen to provide contemporary insight into the next who classification of odontogenic cysts, tumors, and allied. All books are in clear copy here, and all files are secure so dont worry about it. Morgan odontogenic tumors comprise a range of disorders of growth, from malignant and benign neoplasms, to malformations of dental tissues of. From this selection, all the other forms of lesions found in the oral cavity were excluded, in addition to all the record charts to which the histopathological report was not attached, making it impossible to recognize the conclusive diagnosis, even if the diagnostic hypothesis were some type of odontogenic tumor. In general, odontogenic tumors only occur in the jaws, but they have been reported in toothbearing tissues in such structures as dermoid cysts and teratomas. Clinical, radiological and histological features of. Accurate identification of odontogenic tumors is critical for productive.
Odontogenic tumours are rare lesions and many nonspecialist histopathologists will not have seen many during their working lifetime. Calcifying epithelial odontogenic tumors adenomatoid odontogenic tumor. Biological profile based on 100 cases from the literature and own files. An abnormal space within tissue lined by epithelium odontogenic cysts. The nomenclature of odontogenic and nonodontogenic cysts of the oral region is varied.
Our knowledge and understanding continues to evolve and it is clearly time for a more contemporary classification and discussion of odontogenic tumors. Odontogenic tumors encompass a group of lesions that share a common origin from odontogenic tissues. Recently, the classification and nomenclature of odontogenic tumours has been updated. Adenomatoid odontogenic tumors pdf adenomatoid odontogenic tumor aot, a benign hamartomatous lesion of odontogenic origin, is an uncommon tumor which affects mainly. International collaborative study on ghost cell odontogenic. Clinical, radiological and therapeutic features of keratocystic odontogenic tumours. Odontogenesis, odontogenic cysts, and odontogenic tumors. Chapter 21 odontogenic and non odontogenic tumors of the jaws introduction. The latest who classification of odontogenic tumors was published in pathology and genetics.
As our knowledge of disease improves, its classification continually evolves. Table 1 relative frequency % of various odontogenic tumours by geographic location type usa6 china7 nigeria5 odontoma 68 7 4 ameloblastoma 19. Adenomatoid odontogenic tumor aot is a wellestablished benign epithelial lesion of odontogenic origin. Odontogenic tumors are a heterogeneous group of lesions of diverse clinical behavior and histopathologic types, ranging from hamartomatous lesions to malignancy. If squamous odontogenic cystlike proliferations are noted, they should essentially be ignored and are of no prognostic. This site is like a library, you could find million book here by using search box in the header. Maxillary calcifying epithelial odontogenic tumor with. Proceedings of the 36th world small animal veterinary congress 2011. Odontogenic tumours are broadly classified into benign and malignant odontogenic tumours. The ceot is a benign odontogenic tumor of epithelial origin that accounts for approximately 1% of all odontogenic tumors and characteristically contains calcifying masses or homogeneous acellular material within. Odontogenic tumors comprise a complex group of lesions with varied histopathological and clinical features. Oralsurgery 548 dentalupdate julyaugust 2015 odontogenic cysts an overview abstract. Of these diagnoses, 51% were keratocystic odontogenic tumors kcots. Odontogenic tumours are rare lesions and many nonspecialist.
There are many types of cysts of the jaws, but what makes the odontogenic keratocyst unusual are its characteristic histopathological and clinical features, including potentially aggressive behaviour, high recurrence rate, and an association with the nevoid basal cell carcinoma syndrome. Of the odontogenic tumours, the epithet lial and in the bone related types, the fibroosseous lesions were frequent. Seven hundred fiftynine cases of odontogenic tumors retrieved from the files of college of stomatology, west china university of medical sciences were. Due to its aggressive nature, this lesion was renamed as keratocystic odontogenic tumour kcot and reclassified as an odontogenic neoplasm in the histological classification of odontogenic. Calcifying epithelial odontogenic tumor ceot is a rare benign neoplasia, locally aggressive, that tends to invade bone and adjacent soft tissues. They may arise from the epithelial part of the tooth germ, the mesenchymal part or from both.
These include the calcifying epithelial odontogenic tumor pindborg. Odontogenic keratocyst of the posterior maxilla report of an. Odontogenic tumours ot are exclusive to the jaws, as they are derived from epithelial and mesenchymal elements that are part of the tooth forming apparatus. Extramedullary plasmacytomas arise outside of bone, are typically mucocutaneous in location and occur most commonly in the mouth, on the feet or trunk and in the ears.
Odontogenic tumoursan update current diagnostic pathology. There is a variance in the frequency of the various types of ot geographically 46. Ameloblastomaderived from the remnants of the dental lamina benign yet locally agressive most common site is the posterior mandible avg age 38 years very aggressive and grows quite. Osteosarcomas occur more commonly in the appendicular than axial skeleton. Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by. Some are composed only of odontogenic epithelium, while many are mixed i. Historically who benign odontogenic tumor classification from 1971 to 2017.
Keratocystic odontogenic tumour of lesions treated in our clinic. Aot is a relatively uncommon lesion constituting around 3% of all odontogenic tumours and often misdiagnosed as an odontogenic cyst. Nov 20, 2014 the last who classification of odontogenic tumors was 9 years ago and it is time for revision. The hallmark of the tumor is single file cords and strands of. Treatment consisted of enucleation and curettage for 22 of the lesions, resection. The 2005 who classification of odontogenic tumours re. Ameloblastoma, a type of odontogenic tumor involving ameloblasts. Odontogenic tumor definition of odontogenic tumor by. As in all common odontogenic cysts, squamous odontogenic tumorlike proliferations may be seen in longstanding lesions. Due to its aggressive nature, this lesion was renamed as keratocystic odontogenic tumour kcot and reclassified as an odontogenic neoplasm in the histological classification of odontogenic tumours by the world health organization in 2005. It has two clinicopathologic variants, namely intraosseous follicular and. These new views will be incorporated in this article where appropriate. Who histological classification of tumours of the oral cavity and mobile tongue who histological classification of tumours of the oropharynx base of tongue, tonsils, adenoids odontogenic carcinomas.
The aim of this study was to establish the impact of the redefinition and reclassification of odontogenic keratocyst okc as a tumour on the prevalence of odontogenic tumours ot. Nonodontogenic tumours of the jaw originating from bone and its mesenchymal tissue represent a large heterogeneous group of diverse diseases. We revised 15 435 files of a teaching head and neck histopathology service in the time period from january 1981 to december 2008 and 478 cases of ot were selected. Odontogenic tumors comprise a range of disorders of growth, from malignant and benign neoplasms, to malformations of dental tissues of selflimited growth. Morgan odontogenic tumors comprise a range of disorders of growth, from malignant and benign neoplasms, to malformations of dental tissues of selflimited growth. Treatment consisted of enucleation and curettage for 22 of the lesions, resection for 2 and marsupialization for 3. Infraorbital, posterior superior, nasopalatine and greater palatine nerve block was given. Tumors are also called neoplasms, which means that they are composed of new and actively growing tissue.
Introduction a cyst is an epithelium lined sac containing fluid or semifluid material the epithelial cells first proliferate and later undergo degeneration and liquefaction grow by expansion, causing displacement of adjacent teeth. Not only does aot predominantly present radiologically as a unilocular cystic lesion enclosing the unerupted tooth which is commonly mistaken as a. Because odontogenic tumors arise from the tissues which make our teeth, they are unique to the jaws, and by extension almost unique to dentistry. Chapter 21 odontogenic and nonodontogenic tumors of the jaws introduction. A 19year audit of benign jaw tumours and tumourlike lesions. Dec 03, 2019 the glandular odontogenic cyst goc is a very rare and relatively new entity. The term odontogenic keratocyst was first used by philipsen in 1956 1. The sample was obtained from the files of patients with odontogenic. In the whoiarc classification of head and neck pathology, this clinical entity had been known for years as the odontogenic keratocyst. Non odontogenic tumours of the jaw originating from bone and its mesenchymal tissue represent a large heterogeneous group of diverse diseases. Who histological classification of tumours of the oral cavity. Who histological classification of tumours of the oral. Jan 21, 2008 the 2005 who classification of odontogenic tumours re.
They are principally jaw lesions but some may present as localized gingival. A study of 120 cases in an indian teaching hospital article pdf available in medicina oral, patologia oral y cirugia bucal 167. The 2005 who histological classification of odontogenic tumors lays out a classification system for neoplasms and other tumors related to the odontogenic apparatus. Odontogenic tumor odontogenic keratocyst keratinocystic odontogenic tumor three important things associated with this diagnosis. They are principally jaw lesions but some may present as localized gingival swellings, socalled peripheral odontogenic tumors. Odontogenic keratocyst of the posterior maxilla report of. Nomenclature and classification of odontogenic tumors part ii. In other words, odontogenic tumors arise from odontogenic tissues. Using hospital case files and register, we carried out a 15year retrospective study of odontogenic tumours at the dental and maxillofacial. The odontogenic keratocyst is a very well known odontogenic cyst. Reclassification of odontogenic keratocyst as tumour. Clinical, radiological and therapeutic features of. This book greatly expands the body of knowledge in the field of odontogenic tumor pathology. The glandular odontogenic cyst goc is a very rare and relatively new entity.
Any information contained in this pdf file is automatically generated from digital material submitted to epos by third parties in the form of scientific presentations. Nov 20, 2014 the latest who classification of odontogenic tumors was published in pathology and genetics. New findings and controversies in odontogenic tumors. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes examples include. It also highlights the reclassification of odontogenic keratocysts to keratocystic odontogenic tumours. Due to significant characteristics, they differ from bone tumours seen elsewhere in the skeleton. Some tumors are true neoplasms, while some are hamartomas developmental malformations. It describes the epidemiologic, radiologic, and histopathologic features of presently known neoplasms and hamartomatous or tumorlike lesions arising from the toothforming structures, as well as a number of distinctive jaw lesions that must be distinguished from odontogenic tumors. Keratocystic odontogenic tumour, odontogenic keratocyst, odontogenic cysts, keratocyst, carnoys solution. First reported in 1987, by padaychee and van wyk, it was initially called a sialodontogenic cyst. World health organization classification of tumours pathology and genetics of head and neck tumours lyon, iarc press. A calcifying epithelial odontogenic tumor is usually from impacted teeth and looks like a bullseye target from concentric calcific deposits. There are many types of cysts of the jaws, but what makes the odontogenic keratocyst unusual are its characteristic histopathological and clinical features, including potentially aggressive.
Who histological classification of odontogenic tumours 1. A thirteenyear retrospective analysis of 179 odontogenic tumours in a nigerian tertiary healthcare facility b fomete1, od osunde2, jo ogbeifun3 abstract background. Files of patients younger than 20 years of age diagnosed over a period of 26 years with odontogenic tumours were retrieved and analysed for gender, site, tumour size and radiographic appearance. Odontogenic tumors ots are lesions that develop exclusively on maxillary bones. Seventyeight cases of odontogenic tumors were surveyed.
Odontogenic and non odontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. Review critical evaluation of the radiological and. By 1992, however, it had become obvious that this cyst is not salivary but odontogenic in origin and as such the name was changed to glandular odontogenic cyst. Pdf one hundred and twentyseven cases of histologically confirmed odontogenic tumors were retrieved from a total of 5289 oral and maxillary lesions. Odontogenic tumours occur in our environment and because of late treatment, cause considerable disabilities. At the time of writing 2016, it is still the most widely used classification system although a new revision is due to come up in 2017.
These epithelial islands will be cytopathologically benign without evidence of dysplasia. Pathogenesis and nomenclature of odontogenic carcinomas. Odontogenic and nonodontogenic tumors of the jaws are a relatively rare and heterogeneous group of benign and malignant neoplasms, hamartomas, and other bonerelated lesions that demonstrate great variability in etiology, biologic behavior, and clinical significance. The purpose of this study is to analyse in detail the radiological features of aots described in the literature, and to add. Seven hundred fiftynine cases of odontogenic tumors retrieved from the files of college of stomatology, west china university of medical sciences were classified according to the world health.
There was greater number of odontogenic tumours 417 69. Aug 11, 2009 the odontogenic keratocyst is a very well known odontogenic cyst. Relation to gorlin syndrome odontogenic keratocyst can be in the location of any odontogenic cyst. Surgery was planned under sedation and local anesthesia. Pdf download for nomenclature and classification of odontogenic. Research odontogenic tumours manifesting in the first two. There were 18 lesions in the posterior mandible, 3 in the anterior mandible and 6 in the posterior maxilla fig.
Home training materials a digital manual for the early diagnosis of oral neoplasia who histological classification of odontogenic and maxillofacial bone tumours who histological classification of odontogenic and maxillofacial bone tumours 4th edition, 2017. We revised 15 435 files of a teaching head and neck histopathology service in the time period from january 1981 to december 2008 and 478 cases of ot. In this chapter, only those composed of both odontogenic epithelium and mesenchyme will be dealt with, separate chapters being devoted to the. This case report describes the thirteenth known case of ceot with maxillary sinus extension and the second one that also involves the buccal vestibule mucosa with peculiar histopathological and immunohistochemical data.
We offer the following critique as a constructive, thought provoking challenge to those chosen to provide contemporary insight into the next who classification of odontogenic cysts, tumors, and allied conditions. View enhanced pdf access article on wiley online library html view. Odontogenic keratocysts make up around 19% of jaw cysts. Tumours of odontogenic origin ots resulting from epithelial and mesenchymal elements that are part of the toothforming apparatus must be considered as a differential. Pdf odontogenic tumors are a heterogeneous group of lesions of diverse clinical behavior and histopathologic types, ranging from hamartomatous lesions.
This article aims to discuss the clinical features, radiological assessment, histopathology and management of a variety of odontogenic cysts. Head and neck tumours in 2005,1 there were several modifications. Their behaviour varies from neoplastic to hamartomatous. Odontogenic tumors are a heterogeneous group of lesions of diverse clinical. Odontogenic tumours are derived from these toothforming tissues, either the epithelial or the ectomesenchymal or both. Adenomatoid odontogenic tumor aot is an uncommon tumor of odontogenic origin. Odontogenic carcinomas are the malignant epithelial odontogenic neoplasms which comprise the first category of the 2005 who classification of odontogenic tumours. Crevicular incision was taken and site was exposed. An odontogenic tumor is a neoplasm of the cells or tissues that initiate odontogenic processes.